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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
10
Human Site:
T1240
Identified Species:
16.92
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
T1240
A
G
G
R
G
R
L
T
E
E
E
E
A
E
P
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
T1240
A
G
G
R
G
R
A
T
E
E
E
E
A
E
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
G919
E
E
E
E
A
D
P
G
T
E
V
D
L
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
P1445
S
G
G
L
P
R
T
P
G
R
D
F
S
F
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
A876
L
P
V
P
L
A
P
A
G
G
A
G
G
R
E
Chicken
Gallus gallus
Q5F3P8
2008
223067
S1402
S
S
H
P
L
G
K
S
Q
S
T
D
T
V
P
Frog
Xenopus laevis
Q66J90
1938
216239
P1434
K
K
S
S
V
D
E
P
D
E
K
S
F
K
E
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
Q1313
S
P
F
S
Y
P
A
Q
S
P
V
L
S
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
E1190
I
N
E
F
G
P
H
E
E
G
D
V
L
T
N
Honey Bee
Apis mellifera
XP_395451
1406
159180
S995
S
Q
Q
S
P
K
N
S
Q
A
S
Q
V
F
M
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
T1096
H
E
Y
H
P
F
T
T
E
H
C
Y
F
G
I
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
S1489
S
D
S
E
S
S
D
S
D
E
D
D
V
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
V669
N
D
E
G
I
T
R
V
S
K
E
H
D
E
E
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
K902
P
K
K
K
A
K
A
K
K
K
S
K
K
Q
I
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
93.3
N.A.
6.6
N.A.
20
N.A.
N.A.
0
6.6
6.6
0
N.A.
13.3
0
13.3
13.3
P-Site Similarity:
100
93.3
N.A.
13.3
N.A.
40
N.A.
N.A.
0
33.3
26.6
13.3
N.A.
20
33.3
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
15
8
22
8
0
8
8
0
15
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
15
0
0
0
15
8
0
15
0
22
22
8
0
0
% D
% Glu:
8
15
22
15
0
0
8
8
29
36
22
15
0
29
22
% E
% Phe:
0
0
8
8
0
8
0
0
0
0
0
8
15
15
0
% F
% Gly:
0
22
22
8
22
8
0
8
15
15
0
8
8
8
15
% G
% His:
8
0
8
8
0
0
8
0
0
8
0
8
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
15
% I
% Lys:
8
15
8
8
0
15
8
8
8
15
8
8
8
8
0
% K
% Leu:
8
0
0
8
15
0
8
0
0
0
0
8
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
8
15
0
15
22
15
15
15
0
8
0
0
0
0
22
% P
% Gln:
0
8
8
0
0
0
0
8
15
0
0
8
0
8
0
% Q
% Arg:
0
0
0
15
0
22
8
0
0
8
0
0
0
8
0
% R
% Ser:
36
8
15
22
8
8
0
22
15
8
15
8
15
0
0
% S
% Thr:
0
0
0
0
0
8
15
22
8
0
8
0
8
8
8
% T
% Val:
0
0
8
0
8
0
0
8
0
0
15
8
15
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _